Abstract
Leucine rich repeat kinase 2 (LRRK2) was recently identified in genome-wide
association studies (GWAS) as a major susceptibility gene for Crohn’s di…
Abstract
Synthetic Antigen Binders (sABs) are a new class of antibody-based reagents engineered using novel phage display libraries. Using the power of phage …
Abstract
In an aging society, the world is facing severe socio-economic burden of neurodegenerative disease such as Alzheimer’s, Parkinson’s and Huntington…
Abstract
C
D4+ T lymphocytes play important regulatory roles in the adaptive immunity. Upon activation, naïve CD4+ helper T (TH) cells differentiate into effe…
Abstact
The development of metabolic syndrome in obesity and its ultimate manifestation in the forms of cardiovascular diseases and diabetes has become a majo…
Abstract
Metabolic disorders have become a worldwide epidemic that increasingly threatens human health, causing conditions including type 2 diabetes, cardiova…
Abstract
Structural specializations enable von Willebrand factor (VWF) to assemble during biosynthesis into helical tubules in Weibel-Palade bodies (WPB). Spe…
